Lung function in premenopausal, postmenopausal women can decline due to obesity

Obesity has been shown to affect the risk of airway obstructive diseases and can lead to a decline in lung function. A new study suggested that abdominal obesity may result in a greater risk of chronic obstructive pulmonary disease (COPD) and asthma in premenopausal and postmenopausal women.

The study was published in the journal ‘The North American Menopause Society’ (NAMS).

According to previous studies, women experience greater lung function impairment and have a higher risk of developing COPD than men, despite less exposure to smoke. Female smokers experience a more rapid decline in lung function between 45 and 50 years of age, compared with male smokers. The hospitalisation rate of asthma is also higher in women than in men. It is also believed that female hormones contribute to the greater incidence of asthma in women.

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The incidence of COPD in people who are obese is significantly higher than in those of normal weight. In addition, women who are obese are more likely to experience asthma than men who are obese.

Until now, little has been known about the effects of obesity on COPD and asthma in women before and after menopause. This new study, based on data collected from more than one million women, aimed to determine the effect of BMI and waist circumference on COPD and asthma development in premenopausal and postmenopausal women.

The researchers concluded that, regardless of menopause status, high BMI and waist circumference were found to significantly increase the risk of COPD and asthma. Moreover, the higher the BMI and waist circumference, the greater the risk. In addition, being underweight was also identified as a risk factor for COPD in postmenopausal women, suggesting that controlling weight and maintaining a healthy body shape are key to helping prevent COPD and asthma in women.

Study results were published in the article “Obesity and abdominal obesity are risk factors for airway obstructive diseases in Korean women: nationwide population-based cohort study.”

“This study highlights yet another detrimental effect of obesity and abdominal adiposity in women and specifically identified that women with a high BMI and/or waist circumference had a greater risk of developing COPD and asthma. In addition to avoiding tobacco use, maintaining a healthy body weight and composition may help reduce the incidence of COPD and asthma in women,” said Dr Stephanie Faubion, NAMS medical director.

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