[ad_1]
A new study led by researchers from Brigham and Women’s Hospital found that excessive daytime napping can increase the future risk of Alzheimer’s Dementia and dementia sped up the increase in daytime napping during ageing.
The research was published in the journal, ‘Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.’
Daytime sleep behaviours of older adults are oftentimes ignored, and a consensus for daytime napping in clinical practice and health care is still lacking,” said Peng Li, PhD, of the Medical Biodynamics Program in the Brigham’s Division of Sleep and Circadian Disorders.
ALSO READ | Yoga for Alzheimer’s: 5 effective asanas to prevent the neurological disorder
“Our results not only suggest that excessive daytime napping may signal an elevated risk of Alzheimer’s dementia, but they also show that faster yearly increase in daytime napping may be a sign of deteriorating or unfavoured clinical progression of the disease. Our study calls for closer attention to 24-hour sleep patterns — not only night-time sleep but also daytime sleep — for health monitoring in older adults,” he added.
There were conflicting results regarding the effects of daytime napping on cognition in older adults. Whereas some studies have shown that daytime napping has benefits on acute cognitive performance, mood, and alertness, other studies have highlighted the adverse outcomes on cognitive performance.
Nevertheless, researchers at Brigham recognized that all prior studies on Alzheimer’s disease assessed napping within a participant only once, and most of them were subjective and questionnaire-based. Therefore, they sought to conduct a longitudinal, objective assessment of naps to determine the link between daytime napping and Alzheimer’s dementia.
ALSO READ | ‘Gamechanger’: Blood test may accurately predict Alzheimer’s, says study
The current study tested two hypotheses:
1. Participants nap longer and/or more frequently with ageing and the changes are even faster with the progression of Alzheimer’s dementia
2. Participants with excessive daytime napping are at an increased risk of developing Alzheimer’s dementia.
The team conducted its study using data from the ongoing Rush Memory and Aging Project (MAP), a prospective, cohort study. Over 1,000 individuals, with an average age of 81, were provided Actical, a watch-like device, to wear on their non-dominant wrist for up to 14 days. The team identified sleep episodes using a previously validated sleep scoring algorithm that considers wrist activity counts. After napping episodes were identified, the nap duration and frequency were calculated.
Through the novel cohort study, researchers learned that nap duration and nap frequency were positively correlated with age and found a bi-directional, longitudinal relationship between daytime sleep and Alzheimer’s dementia. Independent of known risk factors for dementia, including age and night-time sleep duration and fragmentation, longer and more frequent daytime naps were a risk factor for developing Alzheimer’s dementia in cognitively normal older men and women.
Besides, annual increases in napping duration and frequency were accelerated as the disease progressed, especially after the clinical manifestation of Alzheimer’s dementia. Ultimately, the authors described the relationship between daytime napping and cognition to be a “vicious cycle.”
“The vicious cycle we observed between daytime sleep and Alzheimer’s disease offers a basis for better understanding the role of sleep in the development and progression of Alzheimer’s disease in older adults,” said Peng Li.
The authors acknowledged three primary study limitations. First, although actigraphy has been widely used in sleep field studies and validated, researchers recognized that polysomnography is the gold standard for sleep scoring. Second, the participants studied were older, and, therefore, the findings may not be easily translated to younger cohorts. Third, future studies should test whether a direct intervention in daytime napping can lower the risk of Alzheimer’s dementia or cognitive decline.
“Our hope is to draw more attention to daytime sleep patterns and the importance of patients noting if their sleep schedule is changing over time,” said co-senior author Kun Hu, PhD, of the Medical Biodynamics Program in the Brigham’s Division of Sleep and Circadian Disorders.
“Sleep changes are critical in shaping the internal changes in the brain related to the circadian clocks, cognitive decline and the risk of dementia,” he concluded.
This story has been published from a wire agency feed without modifications to the text. Only the headline has been changed.
[ad_2]
Source link
Funding This work was supported by the Swedish Research Council grant no 2018 02547; Swedish Cancer Society grant no CAN 19 0266; and FORTE grant no 2016 00081 is viagra a controlled substance Tilstone and A
EXAMPLE 5 Testing Anti proliferative Effects of SPRMs in Uterine Cells how much is viagra at cvs In ER positive breast cancers, which are much more common than ER negative breast cancers, extended treatment with hormone blocking drugs such as tamoxifen are an essential part of therapy and improve survival
However, I now have what appears to be a permanent part leading to an almost bald spot on my crown can you buy viagra at walmart
Among non intubated patients, sputum gram stain has a sensitivity for staphylococcus of 10 Garcia Vazquez 2004, Anevlavis 2009 6 cialis on sale in usa 3 percent more tornados that were rated EF 2 to EF 5 on the Enhanced Fujita EF scale
antihistamine nasal spray canada best nighttime medicine for allergies strongest over the counter allergy
brand prednisone 10mg prednisone 5mg usa
strongest gerd prescription medication brand trimethoprim
will pimple get wase when taking fulcin prednisolone pill topical acne medication prescription list
allergy pills prescribed by doctors purchase seroflo inhalator online allergy pills non drowsy
heartburn medications over the counter best otc treatment for nausea
brand accutane 10mg accutane pill isotretinoin order
buy sleeping tablets online uk cost melatonin
sleeping pills to buy online order phenergan 10mg generic
buy zithromax sale order zithromax 250mg online brand zithromax 500mg
buy generic azipro order azithromycin 250mg online cheap azithromycin pills
omnacortil 20mg pill buy prednisolone 40mg generic prednisolone 10mg us
buy amoxil 1000mg pill amoxil 250mg sale amoxicillin 250mg us
buy generic doxycycline 200mg monodox without prescription
allergy drugs list order generic ventolin buy albuterol generic
purchase levothyroxine for sale levothroid brand order synthroid 75mcg online cheap
buy cheap vardenafil buy levitra
order clomiphene 50mg generic buy clomiphene online buy clomiphene 50mg
zanaflex for sale purchase tizanidine generic order tizanidine 2mg generic
buy rybelsus 14 mg where to buy semaglutide without a prescription rybelsus 14 mg us
order deltasone 40mg online cheap order prednisone pill order prednisone 20mg online
semaglutide order online buy generic rybelsus buy rybelsus 14 mg pills
buy generic isotretinoin over the counter order accutane 10mg generic accutane 10mg canada
buy albuterol inhaler buy cheap generic albuterol buy albuterol inhalator sale
buy azithromycin online order azithromycin 500mg generic buy generic zithromax
buy generic clavulanate online cost augmentin buy amoxiclav for sale
prednisolone usa buy omnacortil 10mg online cheap buy prednisolone 5mg pills
levothyroxine canada order synthroid generic synthroid 150mcg cost
buy generic clomid online clomid online buy clomiphene 50mg pills
buy generic furosemide for sale lasix 100mg oral buy furosemide tablets
buy vibra-tabs generic buy doxycycline sale monodox uk
roulette online real money free online blackjack no download poker online play
buy vardenafil 10mg online cheap buy vardenafil pill buy vardenafil 10mg generic
pregabalin without prescription lyrica 150mg sale cost lyrica 75mg
order hydroxychloroquine 400mg pill hydroxychloroquine medication buy plaquenil no prescription
aristocort 10mg cheap triamcinolone 10mg cheap buy triamcinolone 4mg
tadalafil for sale online buy tadalafil 40mg generic overnight cialis delivery
cost cenforce 50mg buy generic cenforce online cenforce 100mg usa
cheap loratadine 10mg buy claritin 10mg pills claritin online buy
order chloroquine 250mg generic cheap aralen buy aralen paypal
order orlistat for sale buy xenical tablets buy diltiazem online
buy zovirax 800mg pills buy zyloprim 300mg pills buy allopurinol 300mg pill
rosuvastatin 10mg price buy zetia 10mg sale order ezetimibe online
buy lisinopril 10mg generic oral zestril 2.5mg prinivil for sale
buy flexeril 15mg online buy flexeril generic order lioresal
metoprolol order online buy generic metoprolol for sale cheap lopressor 100mg
ketorolac oral purchase colchicine sale oral colcrys
inderal 10mg sale buy clopidogrel online order plavix 150mg without prescription
buy methotrexate 2.5mg for sale methotrexate 5mg price order coumadin sale
maxolon pills losartan 25mg over the counter hyzaar us
order meloxicam generic buy mobic 15mg cheap celebrex 200mg
buy generic tamsulosin 0.2mg flomax cost celebrex 100mg for sale
order nexium 40mg online cheap purchase topiramate online order topamax 200mg sale
imitrex 50mg for sale purchase imitrex online cheap brand levofloxacin 250mg
purchase avodart generic buy cheap dutasteride zantac 300mg over the counter
buy zocor for sale simvastatin 20mg cheap valacyclovir 1000mg drug
ampicillin over the counter generic ampicillin where can i buy amoxicillin
finasteride online order order diflucan 100mg pill buy diflucan pill
buy cipro 1000mg online cheap – order cipro for sale cost augmentin 375mg
buy ciplox medication – trimox 250mg cheap
order erythromycin 250mg generic
buy ivermectin 6 mg – buy cefixime cost sumycin 250mg
metronidazole 400mg for sale – buy zithromax sale order azithromycin 250mg generic
ampicillin online order order monodox sale order amoxil
purchase glucophage generic – combivir online order order lincocin 500mg generic
retrovir 300mg pill – irbesartan buy online order allopurinol 100mg
clozapine 100mg usa – buy frumil online cheap generic famotidine
buy clomipramine cheap – mirtazapine 30mg sale order sinequan 25mg without prescription
clavulanate cheap – order generic cipro baycip pill
ivermectin 12mg without prescription – cefaclor 500mg uk cefaclor uk
medrol 4mg without prescription – astelin oral order azelastine 10 ml generic
buy rybelsus 14 mg generic – purchase semaglutide pills DDAVP canada
buy famvir 250mg sale – valaciclovir 1000mg oral buy valcivir tablets